Dental implants in a patient with Paget disease under bisphosphonate treatment: a case report.
Identifieur interne : 005820 ( Main/Exploration ); précédent : 005819; suivant : 005821Dental implants in a patient with Paget disease under bisphosphonate treatment: a case report.
Auteurs : Jesús Torres [Espagne] ; Faleh Tamimi ; Ignacio Garcia ; Alicia Herrero ; Bego A Rivera ; Jose Andrés Sobrino ; Gonzalo HernándezSource :
- Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics [ 1528-395X ] ; 2009.
Descripteurs français
- KwdFr :
- Acide étidronique (administration et posologie), Acide étidronique (analogues et dérivés), Acide étidronique (usage thérapeutique), Administration par voie orale, Adulte d'âge moyen, Agents de maintien de la densité osseuse (administration et posologie), Agents de maintien de la densité osseuse (usage thérapeutique), Femelle, Humains, Maladie de Paget des os (), Maladie de Paget des os (traitement médicamenteux), Maxillaire, Mâchoire partiellement édentée (), Mâchoire partiellement édentée (rééducation et réadaptation), Pose d'implant dentaire endo-osseux, Prothèse dentaire implanto-portée, Prothèse partielle fixe, Risédronate de sodium.
- MESH :
- administration et posologie : Acide étidronique, Agents de maintien de la densité osseuse.
- analogues et dérivés : Acide étidronique.
- rééducation et réadaptation : Mâchoire partiellement édentée.
- traitement médicamenteux : Maladie de Paget des os.
- usage thérapeutique : Acide étidronique, Agents de maintien de la densité osseuse.
- Administration par voie orale, Adulte d'âge moyen, Femelle, Humains, Maladie de Paget des os, Maxillaire, Mâchoire partiellement édentée, Pose d'implant dentaire endo-osseux, Prothèse dentaire implanto-portée, Prothèse partielle fixe, Risédronate de sodium.
English descriptors
- KwdEn :
- Administration, Oral, Bone Density Conservation Agents (administration & dosage), Bone Density Conservation Agents (therapeutic use), Dental Implantation, Endosseous, Dental Prosthesis, Implant-Supported, Denture, Partial, Fixed, Etidronic Acid (administration & dosage), Etidronic Acid (analogs & derivatives), Etidronic Acid (therapeutic use), Female, Humans, Jaw, Edentulous, Partially (complications), Jaw, Edentulous, Partially (rehabilitation), Maxilla, Middle Aged, Osteitis Deformans (complications), Osteitis Deformans (drug therapy), Risedronate Sodium.
- MESH :
- chemical , administration & dosage : Bone Density Conservation Agents, Etidronic Acid.
- chemical , analogs & derivatives : Etidronic Acid.
- chemical , therapeutic use : Bone Density Conservation Agents, Etidronic Acid.
- complications : Jaw, Edentulous, Partially, Osteitis Deformans.
- drug therapy : Osteitis Deformans.
- rehabilitation : Jaw, Edentulous, Partially.
- Administration, Oral, Dental Implantation, Endosseous, Dental Prosthesis, Implant-Supported, Denture, Partial, Fixed, Female, Humans, Maxilla, Middle Aged, Risedronate Sodium.
Abstract
Paget disease (PD) is an idiopathic disorder characterized by progressive enlargement and deformity of bones, resulting in structural weakness that may be unfavorable for the placement of osseointegrated dental implants. Currently, bisphosphonates are administered for the treatment of PD. However, the use of bisphosphonates has been associated with the onset of osteonecrosis of the jaws. This report deals with a case of a 64-year-old caucasian woman diagnosed with polyostotic PD 17 years earlier who had been treated with bisphosphonates for 7 years. The patient was referred for implant treatment, and after initial placement of 6 fixtures, the postoperative course was uneventful and no complications were registered during a follow-up period of 4 years. Within the limitations of this case, we report that dental implants can be successfully placed and loaded in patients suffering from PD without discontinuing the treatment with bisphosphonates, as long as the patient is not complaining from any additional unfavorable conditions. To the best of our knowledge, this is a unique case describing the successful placement of dental implants in a patient with PD treated with bisphosphonates. Nevertheless, more studies would be needed to optimize the clinical guidelines for the treatment of these patients.
DOI: 10.1016/j.tripleo.2008.11.024
PubMed: 19217014
Affiliations:
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Rivera</name></author><author><name sortKey="Sobrino, Jose Andres" sort="Sobrino, Jose Andres" uniqKey="Sobrino J" first="Jose Andrés" last="Sobrino">Jose Andrés Sobrino</name></author><author><name sortKey="Hernandez, Gonzalo" sort="Hernandez, Gonzalo" uniqKey="Hernandez G" first="Gonzalo" last="Hernández">Gonzalo Hernández</name></author></analytic><series><title level="j">Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics</title><idno type="eISSN">1528-395X</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Administration, Oral</term><term>Bone Density Conservation Agents (administration & dosage)</term><term>Bone Density Conservation Agents (therapeutic use)</term><term>Dental Implantation, Endosseous</term><term>Dental Prosthesis, Implant-Supported</term><term>Denture, Partial, Fixed</term><term>Etidronic Acid (administration & dosage)</term><term>Etidronic Acid (analogs & derivatives)</term><term>Etidronic Acid (therapeutic use)</term><term>Female</term><term>Humans</term><term>Jaw, Edentulous, Partially (complications)</term><term>Jaw, Edentulous, Partially (rehabilitation)</term><term>Maxilla</term><term>Middle Aged</term><term>Osteitis Deformans (complications)</term><term>Osteitis Deformans (drug therapy)</term><term>Risedronate Sodium</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Acide étidronique (administration et posologie)</term><term>Acide étidronique (analogues et dérivés)</term><term>Acide étidronique (usage thérapeutique)</term><term>Administration par voie orale</term><term>Adulte d'âge moyen</term><term>Agents de maintien de la densité osseuse (administration et posologie)</term><term>Agents de maintien de la densité osseuse (usage thérapeutique)</term><term>Femelle</term><term>Humains</term><term>Maladie de Paget des os ()</term><term>Maladie de Paget des os (traitement médicamenteux)</term><term>Maxillaire</term><term>Mâchoire partiellement édentée ()</term><term>Mâchoire partiellement édentée (rééducation et réadaptation)</term><term>Pose d'implant dentaire endo-osseux</term><term>Prothèse dentaire implanto-portée</term><term>Prothèse partielle fixe</term><term>Risédronate de sodium</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Bone Density Conservation Agents</term><term>Etidronic Acid</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Etidronic Acid</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Bone Density Conservation Agents</term><term>Etidronic Acid</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Acide étidronique</term><term>Agents de maintien de la densité osseuse</term></keywords><keywords scheme="MESH" qualifier="analogues et dérivés" xml:lang="fr"><term>Acide étidronique</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Jaw, Edentulous, Partially</term><term>Osteitis Deformans</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Osteitis Deformans</term></keywords><keywords scheme="MESH" qualifier="rehabilitation" xml:lang="en"><term>Jaw, Edentulous, Partially</term></keywords><keywords scheme="MESH" qualifier="rééducation et réadaptation" xml:lang="fr"><term>Mâchoire partiellement édentée</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Maladie de Paget des os</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Acide étidronique</term><term>Agents de maintien de la densité osseuse</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Administration, Oral</term><term>Dental Implantation, Endosseous</term><term>Dental Prosthesis, Implant-Supported</term><term>Denture, Partial, Fixed</term><term>Female</term><term>Humans</term><term>Maxilla</term><term>Middle Aged</term><term>Risedronate Sodium</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Administration par voie orale</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Maladie de Paget des os</term><term>Maxillaire</term><term>Mâchoire partiellement édentée</term><term>Pose d'implant dentaire endo-osseux</term><term>Prothèse dentaire implanto-portée</term><term>Prothèse partielle fixe</term><term>Risédronate de sodium</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Paget disease (PD) is an idiopathic disorder characterized by progressive enlargement and deformity of bones, resulting in structural weakness that may be unfavorable for the placement of osseointegrated dental implants. Currently, bisphosphonates are administered for the treatment of PD. However, the use of bisphosphonates has been associated with the onset of osteonecrosis of the jaws. This report deals with a case of a 64-year-old caucasian woman diagnosed with polyostotic PD 17 years earlier who had been treated with bisphosphonates for 7 years. The patient was referred for implant treatment, and after initial placement of 6 fixtures, the postoperative course was uneventful and no complications were registered during a follow-up period of 4 years. Within the limitations of this case, we report that dental implants can be successfully placed and loaded in patients suffering from PD without discontinuing the treatment with bisphosphonates, as long as the patient is not complaining from any additional unfavorable conditions. To the best of our knowledge, this is a unique case describing the successful placement of dental implants in a patient with PD treated with bisphosphonates. Nevertheless, more studies would be needed to optimize the clinical guidelines for the treatment of these patients.</div></front></TEI><affiliations><list><country><li>Espagne</li></country><region><li>Communauté de Madrid</li></region><settlement><li>Madrid</li></settlement></list><tree><noCountry><name sortKey="Garcia, Ignacio" sort="Garcia, Ignacio" uniqKey="Garcia I" first="Ignacio" last="Garcia">Ignacio Garcia</name><name sortKey="Hernandez, Gonzalo" sort="Hernandez, Gonzalo" uniqKey="Hernandez G" first="Gonzalo" last="Hernández">Gonzalo Hernández</name><name sortKey="Herrero, Alicia" sort="Herrero, Alicia" uniqKey="Herrero A" first="Alicia" last="Herrero">Alicia Herrero</name><name sortKey="Rivera, Bego A" sort="Rivera, Bego A" uniqKey="Rivera B" first="Bego A" last="Rivera">Bego A Rivera</name><name sortKey="Sobrino, Jose Andres" sort="Sobrino, Jose Andres" uniqKey="Sobrino J" first="Jose Andrés" last="Sobrino">Jose Andrés Sobrino</name><name sortKey="Tamimi, Faleh" sort="Tamimi, Faleh" uniqKey="Tamimi F" first="Faleh" last="Tamimi">Faleh Tamimi</name></noCountry><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Torres, Jesus" sort="Torres, Jesus" uniqKey="Torres J" first="Jesús" last="Torres">Jesús Torres</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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